Director, Clinical Project Management

Harpoon Therapeutics is a clinical-stage immuno-oncology company focused on the discovery and development of novel, proprietary bispecific T cell engaging biologic drug candidates for the treatment of various cancers. Harpoon’s first product, HPN424, is in clinical development for prostate cancer, and the second product HPN536 is in clinical testing for mesothelin over-expressing tumors, such as lung, pancreatic and ovarian cancers. Harpoon currently has two additional products in development and intends to introduce these into clinical development by the end of 2020. Harpoon is led by an experienced management team and has raised more than $200 million from leading life science investors. The company emphasizes a collegial, collaborative environment and has a strong record of scientific innovation, pioneering protein engineering, expertise in tumor immunology and clinical research.

We are seeking a highly motivated individual to oversee Clinical Project Management. This individual will report into the Sr. Director/P.T.L. and play an essential role in supporting the cross-functional drug development activities of pipeline products at Harpoon. The Director, Clinical Project Management serves as a strategic partner to project team leaders in the execution of the strategic vision of the program. You will drive the development and execution of high quality, integrated cross-functional project plans for one or more products in support of the overall program strategy. In addition, you may be asked to lead and/or participate in special department, cross-functional, or team projects.

Key Responsibilities

  • Identify key deliverables for each function and their inter-dependencies
  • Work with multiple project teams to develop study project plans that delineate team objectives, activities, timelines, and resources required
  • Drive planning for key drug development stage-gate decision points (e.g., First in Human, End of Phase 2, Filing, and Launch)
  • Implement best practices and ensure cross-functional alignment and accountability
  • Identify project issues or resource gaps and facilitate resolution
  • Monitor and communicate progress and adherence to timelines
  • Facilitate resource planning, financial and capacity assessments
  • Conduct risk management, contingency and scenario planning using a variety of project management tools
  • Identify and efficiently resolve issues, driving decisions, and tracking action items
  • Develop strong partnerships with external business partners and strategic alliances, where applicable
  • Serve as a single point of contact for cross-functional project team information (content and quality)
  • Communicate cross-functional project information at project team meetings and to other stakeholders, as appropriate

Skills and Qualifications

  • At minimum, a bachelor's degree in nursing, science or health related field required
  • At least 2 years of oncology experience preferred
  • 5-8 years of project manager experience in drug development, clinical project management experience a must
  • Clinical research knowledge and cross-functional understanding of clinical trial methodology
  • History of motivating others to deliver to important milestones while maintaining a positive, transparent and collaborative team environment
  • Capable of assessing and updating detailed project timelines in meetings to guide and align study team members
  • Ability to establish priorities, operate with a sense of urgency and collaborate (interpersonal, relationship management) with the study team, cross functional team members
  • Ability to evaluate meeting minutes and materials for required updates to project timelines
  • Must display strong analytical and problem solving skills
  • Excellent verbal and written communication, strong organizational and interpersonal skills
  • Ability to work both independently and collaboratively with cross-functional teams
  • Ability to work in a dynamic, fast-paced, timeline-based environment