Gerald McMahon, PhD
President and Chief Executive Officer
Dr. McMahon joined Harpoon in December 2016 bringing more than 25 years of biotechnology leadership, scientific innovation and creative deal-making experience. Dr. McMahon was previously president and CEO of Kolltan Pharmaceuticals, an oncology biologics company acquired by Celldex in 2016, and senior vice president of R&D oncology at MedImmune, the biologics arm of AstraZeneca. He also served as a venture partner at Bay City Capital and in executive leadership roles at Poniard Pharmaceuticals and SUGEN (ultimately acquired by Pfizer), where he was a key player in the development of innovative oncology drugs Sutent® and Palladia®.
Dr. McMahon holds an academic appointment at the Yale Comprehensive Cancer Center at Yale University, and held previous appointments at Tufts University School of Medicine, department of hematology & oncology at the New England Medical Center, and the Massachusetts Institute of Technology. He received his BS in biology and PhD in biochemistry from Rensselaer Polytechnic Institute.
Che-Leung Law, PhD
Vice President, Translational Medicine
Dr. Law joined Harpoon in April 2017 with more than 19 years of experience in the discovery and development of novel biologics and small molecules in oncology and immuno-oncology. Dr. Law most recently was senior director of preclinical research at Seattle Genetics, where he led target discovery, drug technology development, IND-enabling studies, translational research, and pharmacodynamic and biomarker research. Dr. Law previously held scientific positions at CDR Therapeutics and Xcyte Therapies. He was also an affiliate assistant professor in the department of microbiology at the University of Washington for several years. Dr. Law received his PhD in pathobiology from the University of Minnesota and an MPhil in biochemistry from the University of Hong Kong.
William E. Picht, Jr., MBA
Chief Financial Officer
Mr. Picht joined Harpoon in January 2017 with more than 25 years of industry experience in strategic finance, operations, investor relations, business planning and oversight. Prior to Harpoon, he served as chief financial officer for Pearl Therapeutics, a respiratory disease company that was sold to AstraZeneca in a $1.15 billion transaction. At Pearl, Mr. Picht was responsible for finance, administration and information technology. Previously, he served as head of R&D finance at Nektar Therapeutics, and conducted finance and market analytics at Syntex. Mr. Picht received his BA from the University of Notre Dame and his MBA from San Jose State University.
Holger Wesche, PhD
Senior Vice President, Research
Dr. Wesche joined Harpoon Therapeutics with 20 years of biotech experience focused on target validation, drug discovery and drug development as well as multi-site project management in the fields of oncology and inflammation. His previous role was as scientific director at Amgen where he was responsible for cross-functional organization and coordination of the next generation BiTE platform, the industry’s leading T-cell engaging antibody platform. He also led several drug discovery projects through pre-clinical development. Dr. Wesche is co-author of numerous publications and several US patents. Dr. Wesche received his PhD, summa cum laude, in biochemistry and Immunology from the University of Hannover, Germany.